Soluble ST2 for Prognosis and Monitoring in Heart Failure
نویسندگان
چکیده
منابع مشابه
Prognostic Value of Soluble ST2 (sST2) Serum Levels in Infants and Children with Heart Failure Complicating Congenital Heart Disease
Background Heart failure (HF) in infants and children with congenital heart disease (CHD) is a crucial complication with different outcomes. Many biomarkers are used as prognostic indicators. Soluble ST2 (sST2) is one of these markers studied in adults with HF. We aimed to study the prognostic value of sST2 in CHD children with HF. Materials and Methods In current case-control study, thirty-six...
متن کاملSoluble ST2 protein in the short-term prognosis after hospitalisation in chronic systolic heart failure.
BACKGROUND The prognosis in patients with chronic heart failure (CHF) is poor. ST2 protein is a promising prognostic biomarker for CHF. ST2 belongs to the cardioprotective signalling pathway involving interleukin-33 and its concentration in the serum depends on the biomechanical stress of cardiomyocytes (biomechanical strain). AIM To determine the prognostic value of ST2 in short term follow-...
متن کاملSoluble ST2 monitoring provides additional risk stratification for outpatients with decompensated heart failure.
INTRODUCTION AND OBJECTIVES The novel biomarker ST2 provides diagnostic information in a variety of clinical settings. The objective was to determine whether measurement of the soluble ST2 (sST2) concentration improves risk stratification in outpatients with decompensated heart failure (HF). METHODS The concentrations of sST2 and N-terminal probrain natriuretic peptide (NT-proBNP) and a heart...
متن کاملSoluble ST2: A Novel Prognostic Biomarker of Heart Failure.
Previous studies have demonstrated the role of ST2 in predicting hospitalization and mortality in heart failure, independent of natriuretic peptides and other clinical variables. 9-17 In 2011, the U.S. Food and Drug Administration (FDA) delared the Presage ST2 Assay (Critical Diagnostics, San Diego, California, USA), which is typically used in conjunction with clinical evaluation as an aid in a...
متن کاملSoluble ST2 for Prediction of Heart Failure and Cardiovascular Death in an Elderly, Community‐Dwelling Population
BACKGROUND Soluble ST2 (sST2), a marker of myocyte stretch and fibrosis, has prognostic value in many cardiovascular diseases. We hypothesized that sST2 levels are associated with incident heart failure (HF), including subtypes of preserved (HFpEF) and reduced (HFrEF) ejection fraction, and cardiovascular death. METHODS AND RESULTS Baseline serum sST2 was measured in 3915 older, community-dwe...
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ژورنال
عنوان ژورنال: Journal of the American College of Cardiology
سال: 2017
ISSN: 0735-1097
DOI: 10.1016/j.jacc.2017.09.031